^ Robison AJ, Nestler EJ (October 2011). "Transcriptional and epigenetic mechanisms of addiction". Nature Reviews. Neuroscience. 12 (11): 623–37. doi:10.1038/nrn3111. PMC 3272277. PMID 21989194. ΔFosB has been linked directly to several addiction-related behaviors ... Importantly, genetic or viral overexpression of ΔJunD, a dominant negative mutant of JunD which antagonizes ΔFosB- and other AP-1-mediated transcriptional activity, in the NAc or OFC blocks these key effects of drug exposure14,22–24. This indicates that ΔFosB is both necessary and sufficient for many of the changes wrought in the brain by chronic drug exposure. ΔFosB is also induced in D1-type NAc MSNs by chronic consumption of several natural rewards, including sucrose, high fat food, sex, wheel running, where it promotes that consumption14,26–30. This implicates ΔFosB in the regulation of natural rewards under normal conditions and perhaps during pathological addictive-like states.
There are many reasons people get addicted to drugs, but you must gain insight into what draws you towards your substance of choice. Is it a means to cope with stress? Do drugs help numb you emotionally so you don’t have to feel emotional or physical pain? Are drugs a way to avoid responsibility, gain other’s approval or belong to a group? It’s important that you peel back the layers of your behavior to understand what is behind your drug habits. How I overcame alcoholism | Claudia Christian | TEDxLondonBusinessSchool

The help of family members can be absolutely invaluable in terms of supporting the addict through their recovery over the long term after they leave rehab, and they can get support and advice on what they need to do to continue to encourage their loved one through the process of their recovery, how to avoid triggering them, how to help them prevent relapse and various other things which together can make the difference between success and failure in recovery.

While a relapse or slip-up is by no means inevitable, you might face some setbacks during recovery. This does not have to mean returning to alcohol use. A lapse should not signify the end of your recovery, provided you act appropriately, in order to avoid a full relapse. You might even find that this small slip is enough to remind you of why you wanted to quit in the first place. Addiction is a disease. We should treat it like one | Michael Botticelli
Alcohol is a legal controlled substance that slows down the body’s vital functions when consumed in excess. Its many forms include beer, wine and liquor. Some of the physical effects of heavy alcohol consumption are slurred speech, loss of coordination and slowed reaction time. Psychological effects include inhibiting judgment and lowering a person’s ability to think rationally. Typically, drinking alcohol in moderation does not signify a problem. However, consuming more than four alcoholic beverages per day for men – or more than three per day for women – can indicate an alcohol use disorder (AUD).

An individual who suffers from both mental illness and alcoholism will need to undergo different treatment. Because alcohol withdrawal symptoms cause a person to experience some psychiatric stress, an alcoholic with mental health issues will find it much more difficult to resist turning to drink. The NIAAA believes the some self-help groups, such as Alcoholics Anonymous, are not effective when it comes to treating people with a dual-diagnosis of both alcoholism and mental illness. This is because these groups tend to specifically focus on the actual addiction itself, rather than any underlying psychological problems. Anti-depressants are improving all the time and it is believed that while a self-help group may not be useful for a dual-diagnosis individual by itself, if the individual is on the appropriate medication and receiving the appropriate psychological therapy it can prove to be just as effective as with other alcoholic individuals. Addiction Recovery: 12 Steps and Beyond (TTA Podcast 321)


Developing a drug addiction isn’t a character flaw or a sign of weakness, and it takes more than willpower to overcome the problem. Abusing illegal or certain prescription drugs can create changes in the brain, causing powerful cravings and a compulsion to use that makes sobriety seem like an impossible goal. But recovery is never out of reach, no matter how hopeless your situation seems. With the right treatment and support, change is possible. Don’t give up—even if you’ve tried and failed before. The road to recovery often involves bumps, pitfalls, and setbacks. But by examining the problem and thinking about change, you’re already well on your way.
According to the National Institute on Drug Abuse, addiction is a "chronic, relapsing brain disease that is characterized by compulsive drug seeking and use, despite harmful consequences."7  There is no simple cure for addiction; however, effective treatment can help you become and stay sober.7  You will have to manage your addiction throughout your life, the same way a diabetic has to manage their condition with ongoing efforts like a proper diet and exercise.8
Inpatient treatment programs require the patient to live at the facility for the duration—typically 30, 60, or 90 days—of treatment. The process often starts with detoxification. During this time, withdrawal symptoms are managed in a safe environment by qualified medical staff.  Medications may be administered to alleviate or prevent serious symptoms. Drug Rehab Near Me
Behavioral models make use of principles of functional analysis of drinking behavior. Behavior models exist for both working with the substance abuser (Community Reinforcement Approach) and their family (Community Reinforcement Approach and Family Training). Both these models have had considerable research success for both efficacy and effectiveness. This model lays much emphasis on the use of problem-solving techniques as a means of helping the addict to overcome his/her addiction. Drug and Alcohol Treatment Centers ► What You Don't Know
It can be heartbreaking to realize that your loved one has a problem with alcohol. You want to do anything you can to help — but you’re afraid that if you speak up, you could destroy your relationship, or even drive your loved one deeper into addiction. At first, it’s much easier to deny the problem. But as time goes on and personal, financial, or legal problems increase, you’ll have to face the possibility that your loved one could have a substance use disorder. Learning to recognize the red flags of alcoholism could not only save your relationship, it could help you avoid a tragedy.

Biological factors that can affect a person's risk of addiction include their genes, stage of development, and even gender or ethnicity. Scientists estimate that genes, including the effects environmental factors have on a person's gene expression, called epigenetics, account for between 40 and 60 percent of a person's risk of addiction.27 Also, teens and people with mental disorders are at greater risk of drug use and addiction than others.28


Biological factors that can affect a person's risk of addiction include their genes, stage of development, and even gender or ethnicity. Scientists estimate that genes, including the effects environmental factors have on a person's gene expression, called epigenetics, account for between 40 and 60 percent of a person's risk of addiction.27 Also, teens and people with mental disorders are at greater risk of drug use and addiction than others.28
Like any other life-threatening disease, drug addiction requires intensive treatment by credentialed specialists. While some may be able to find recovery alone, true healing is a lifelong process that typically requires continued support. Drug addiction treatment options range from medical detox and inpatient care to 12-step programming, pharmacotherapy and outpatient services. Throughout a continuum of care, patients are offered resources, skills and support to ensure that they’re making progress toward recovery goals.
When a person who is dependent on sleeping pills tries to quit cold turkey, their body may experience withdrawal. Symptoms of withdrawal can be uncomfortable, so it is best to go through the process at a medical detox center. Further treatment at an inpatient rehab center or outpatient program can address the psychological impact of an addiction to sleeping pills.

Drug addiction isn’t always an instantly obvious problem; it often starts small. In fact, drug addiction sometimes begins with simple recreational use, or a “one-time” experiment, trying something new, or even a prescription for a much-needed painkiller after an accident or surgery. The trouble is that for some people—the ones who become addicted—the use of the addictive substance becomes frequent and a necessity.

Don't let financial constraints stop you from living a life free of alcoholism. Regardless of whether you don't have insurance, your insurance benefits ran out, or your insurance refuses to cover your alcohol dependency treatment, you can get treatment. Free alcohol rehabilitation is available if you really want it. By admitting you have a problem and need help you have already completed the first and most important step of pursuing a life of sobriety.
During alcoholism treatment, therapy teams provide lessons on relapse prevention. These lessons are designed to help people spot the people, places, and things that can drive them to return to drinking. With the help of these lessons, people can learn to both avoid and/or handle their triggers so they won’t pick up an alcoholic beverage when they’re under stress. Inpatient Alcohol Rehab | Drug Rehab Treatment | Alcoholism
Inpatient vs Outpatient is an important consideration when choosing a treatment program. If you’re wondering if outpatient treatment is the right choice for you, this article may help you decide. The choice ultimately comes down to your time availability and finances. Can you afford to stop everything in your life for inpatient treatment? If you need to maintain your job and other commitments, outpatient treatment might be the best option for you.
Remember though, overcoming alcoholism is a process. Less than half of individuals relapse after achieving one year of sobriety. That number reduces to less than 15 percent who relapse after five years of sobriety. For the greatest chance of long-term sobriety after completing an inpatient or outpatient program, you should participate in local support groups and continue with counseling. Treating alcoholism is an investment in your future. It will not only make a huge difference in your life, but also the lives of those around you such as family members and friends. Rehab Nightmare: Drugs, Chains and Canes - Full Documentary - BBC Africa Eye
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